{"id":39135,"date":"2024-06-02T09:08:39","date_gmt":"2024-06-02T09:08:39","guid":{"rendered":"https:\/\/drlesliekorn.com\/?post_type=research-databases&p=39135"},"modified":"2025-02-25T09:14:04","modified_gmt":"2025-02-25T09:14:04","slug":"vitamin-d-omega-fatty-acids-autoimmune-disease","status":"publish","type":"research-databases","link":"https:\/\/drlesliekorn.com\/es\/research\/vitamin-d-omega-fatty-acids-autoimmune-disease\/","title":{"rendered":"Vitamin D and Marine Omega-3 Fatty Acids Reduce the Risk of Autoimmune Disease"},"content":{"rendered":"\n

Visit my library: R<\/a><\/strong>esearch in Integrative Medicine and Nutrition for Mental Health<\/strong><\/a><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Autoimmune disease is highly associated with a history of traumatic stress and complex trauma. Lupus, Rheumatoid arthritis, and Hashimoto\u2019s are among the complex diseases of the immune system resulting from being hypervigilant. The immune system then takes up the trauma response and, seeing danger everywhere, names itself the enemy and begins attacking itself. The resulting inflammatory response can also occur in response to food sensitivities, most often gluten and casein, which is why I also recommend an elimination trial of these foods.<\/p>\n\n\n\n

Inflammation also influences the gut and neurotransmitter signaling in brain regions relevant to fear, anxiety, and emotion regulation. All of this suggests several integrative clinical pathways for us to travel toward the resolution of inflammation and autoimmune disease.<\/p>\n\n\n\n

My clients often ask what the two most critical nutritional supports to add to their diet are, and I answer that omega-3 fatty acids and vitamin D.  Vitamin D is a neurohormone and not a vitamin, essential to the absorption of calcium and phosphate from the intestines, synthesis of cholesterol. Optimal vitamin D levels reduce pain, are antidepressant, and support immune function. <\/p>\n\n\n\n

It is rare to find anyone with adequate serum Vitamin D levels who is not supplementing, and everyone living above the 39th parallel should always supplement with Vitamin D.<\/p>\n\n\n\n

A new study with a large cohort (over 20,000 participants) supports the role of supplementary vitamin D (2000 IU\/day) and omega-three fatty acids (1000 mg\/day) as having a 22% reduced risk in autoimmune disease. An additional finding is that to be effective, supplementation must be ongoing as the effects wear off over time. The measures tested were inflammatory markers confirming the anti-inflammatory effects of both D3 and Omegas 3s.<\/p>\n\n\n\n

The preferred form of the vitamin is D3. Combine it with another fat-soluble vitamin, K2\/3. Note that in this research, the dose levels were lower than what we use in clinical practice to optimize both vitamin D and omega-3 fatty acid levels. This suggests that a more optimal clinical dose might bring even better results.  <\/p>\n\n\n\n

Vitamin D is fat soluble so take it with some fat. Following several months of supplementation, if Vitamin D levels do not rise enough, you might consider a genomic test for the Vitamin D receptor polymorphism (VDR), which can reduce cell receptivity to supplementation and thus require higher than normal doses.<\/p>\n","protected":false},"excerpt":{"rendered":"

Visit my library: Research in Integrative Medicine and Nutrition for Mental Health Autoimmune disease is highly associated with a history of traumatic stress and complex trauma. Lupus, Rheumatoid arthritis, and […]<\/p>\n","protected":false},"author":3,"featured_media":39136,"menu_order":21,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":true,"inline_featured_image":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"research-categories":[1538,1539],"class_list":{"0":"post-39135","1":"research-databases","2":"type-research-databases","3":"status-publish","4":"has-post-thumbnail","6":"research-categories-autoimmune-disease","7":"research-categories-supplements","8":"entry"},"acf":[],"yoast_head":"\nVitamin D & Omega-3 Reduce the Risk of Autoimmune Disease<\/title>\n<meta name=\"description\" content=\"A new study supports the role of supplementary vitamin D and omega-three fatty acids as having a 22% reduced risk in autoimmune disease.\" 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