{"id":39475,"date":"2024-06-11T09:08:35","date_gmt":"2024-06-11T09:08:35","guid":{"rendered":"https:\/\/drlesliekorn.com\/?post_type=research-databases&p=39475"},"modified":"2025-02-25T09:16:05","modified_gmt":"2025-02-25T09:16:05","slug":"keto-diet-psychiatry-mental-health","status":"publish","type":"research-databases","link":"https:\/\/drlesliekorn.com\/es\/research\/keto-diet-psychiatry-mental-health\/","title":{"rendered":"The Keto Diet, a Comprehensive Review, its Variants and Therapeutic Potential"},"content":{"rendered":"\n
\"Keto-friendly<\/figure>\n\n\n\n

This week, I am focusing on the Keto diet. The ketogenic diet (70-90% fat in daily diet) was introduced in modern times by Dr. Russell Wilder at the Mayo Clinic in 1921 to treat intractable epilepsy. His goal was to mimic the effects of fasting, which led to ketogenesis, and his clinical work proved successful. <\/p>\n\n\n\n

While the controversy continues about which diet is best for us, the fact is there is no one right diet for everyone. It depends on who we are and what our brain, mind, and body need for nourishment. Nevertheless, there is compelling research on the keto diet, especially for epilepsy and psychotic disorders.  A grain free, low carb diet makes sense for this population since a significant percentage of people with a diagnosis of psychosis are highly reactive to the proteins found in gluten and have been found to have challenges with both brain glucose and phospholipid metabolism. And who doesn’t benefit from a good supply of high-quality fats?<\/p>\n\n\n\n

These papers provide a solid overview of what is known (and not) about how the Keto diet  works and provides descriptions of the four main variants: Classic KD (CKD), Modified Atkins Diet (MAD), Medium Chain Triglyceride Diet (MCT), and Low Glycemic Index Therapy (LGIT) <\/p>\n\n\n\n

These studies suggest the benefits and potential cautions associated with the keto diet. I always encourage my interested clients to try it for 3 months to see if they feel the benefits or if they feel better by adjusting the ratios of fats, proteins, and carbs. <\/p>\n\n\n\n

As I read these studies, I wondered what researchers are making the case against the keto diet. (I maintain every type of diet can work; it just needs to be the right match for the individual.) <\/p>\n\n\n\n

One recent paper I reviewed had fascinating findings, though the full implications are as yet unclear for our clinical practice. By comparing immune responses to the keto or vegan diet and switching from one diet to another, they showed changes to innate immunity versus adaptive immunity, as well as immediate changes in the microbiome. One outcome showed that a vegan diet enhanced the immune system’s antiviral function, suggesting that under viral infection conditions, doing a \u201cvegan cleanse\u201d might be helpful. <\/p>\n","protected":false},"excerpt":{"rendered":"

This week, I am focusing on the Keto diet. 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