{"id":39509,"date":"2024-06-10T09:08:33","date_gmt":"2024-06-10T09:08:33","guid":{"rendered":"https:\/\/drlesliekorn.com\/?post_type=research-databases&#038;p=39509"},"modified":"2025-02-25T09:15:52","modified_gmt":"2025-02-25T09:15:52","slug":"mitochondria-dysfunction-chronic-fatigue-long-covid","status":"publish","type":"research-databases","link":"https:\/\/drlesliekorn.com\/es\/research\/mitochondria-dysfunction-chronic-fatigue-long-covid\/","title":{"rendered":"The Role of Mitochondrial Dysfunction in Chronic Fatigue and Long COVID"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"929\" height=\"1024\" src=\"https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-929x1024.jpeg\" alt=\"\" class=\"wp-image-39510\" srcset=\"https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-929x1024.jpeg 929w, https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-473x522.jpeg 473w, https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-768x847.jpeg 768w, https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-1393x1536.jpeg 1393w, https:\/\/drlesliekorn.com\/wp-content\/uploads\/2024\/05\/mitochondria-dysfuntion-fatigue-long-COVID-1857x2048.jpeg 1857w\" sizes=\"(max-width: 929px) 100vw, 929px\" \/><figcaption class=\"wp-element-caption\">Cells with mitochondria shown in green. Image: National Institute of Child Health (NICHD)<\/figcaption><\/figure>\n\n\n\n<p>Those of you who follow my work know my passion for supporting mitochondria for mental health and the ways in which psychotropic medications can depress mitochondrial respiration. Yes! Even mitochondria do their moment-to-moment pranayama!&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What are Mitochondria?<\/strong><\/h2>\n\n\n\n<p>Mitochondria play a vital role in cellular energy production and overall cellular health. Mitochondrial dysfunction can be due to genetic, environmental, nutritional medication, or age-related influences. These changes disrupt neuronal energy, increase oxidative stress, and promote inflammation.<\/p>\n\n\n\n<p>The first publication of this research post is an example of what happens when multiple studies are reviewed, with multiple designs and methods compared, in order to ascertain an outcome: Results end up being \u00abclear as mud\u00bb, and the authors correctly call for better-designed standardized studies.&nbsp;<\/p>\n\n\n\n<p>However, research needs to reflect bioindividual needs as well. In spite of the mixed conclusions from the first article, clinical observation and plenty of research evidence clearly show that mitochondrial dysfunction is involved in mental illness, chronic pain, fatigue, and post-infectious syndromes like Long COVID. The general agreement focuses on the numerous types of exposure that damage mitochondria and lead to excessive oxidative stress.&nbsp;&nbsp;<\/p>\n\n\n\n<p>The second article explores the role of mitochondrial dysfunction in Long COVID, and potential therapeutic strategies aimed at improving mitochondrial function. It highlights lifestyle changes, exercise, and dietary interventions while stressing the importance of continued research and collaborative efforts to advance our understanding and treatment of Long COVID.<\/p>\n\n\n\n<p>The final article of this post draws links between fatigue, serotonin, and hypothyroidism, suggesting the use of the amino acid L- Carnitine, known for its benefits in mitochondrial support, may play a role in improving outcomes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How to Support Your Mitochondria?<\/strong><\/h2>\n\n\n\n<p>Eating foods associated with the colors of the Brainbow, like plant polyphenols and polyunsaturated fatty acids, improves mitochondrial metabolism and biogenesis and reduces oxidative stress.<\/p>\n\n\n\n<p>Mitochondria relies on B vitamins, Coenzyme Q10, and magnesium to start. <a href=\"https:\/\/drlesliekorn.com\/blog\/photobiomodulation\/\">Photobiomodulation<\/a> also supports mitochondrial function. High-intensity Interval training boosts mitochondria, and reducing exposure to blue lights, which can damage retina-rich mitochondria, is another action to take.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Those of you who follow my work know my passion for supporting mitochondria for mental health and the ways in which psychotropic medications can depress mitochondrial respiration. Yes! Even mitochondria [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":39510,"menu_order":13,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":true,"inline_featured_image":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"research-categories":[1538,1579,1583],"class_list":{"0":"post-39509","1":"research-databases","2":"type-research-databases","3":"status-publish","4":"has-post-thumbnail","6":"research-categories-autoimmune-disease","7":"research-categories-long-covid","8":"research-categories-mitochondria","9":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>The Role of Mitochondrial Dysfunction in Chronic Fatigue and Long COVID | Dr. Leslie Korn<\/title>\n<meta name=\"description\" content=\"Cells with mitochondria shown in green. 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